Mining Surveillance Data: Does Radiation Treatment of Prostate Cancer Cause Rectal Cancer?

Authors

  • John W. Morgan Dept Epidemiology, Biostatistics & Population Medicine, Loma Linda University School of Public Health; Desert Sierra Cancer Surveillance Program, Region 5 of California Cancer Registry
  • Brice Jabo Dept Epidemiology, Biostatistics & Population Medicine, Loma Linda University School of Public Health; Desert Sierra Cancer Surveillance Program, Region 5 of California Cancer Registry
  • Mark E. Ghamsary Dept Epidemiology, Biostatistics & Population Medicine, Loma Linda University School of Public Health
  • Kevork Kazanjian Dept of Surgery, Division of Surgical Oncology, Loma Linda University School of Medicine

DOI:

https://doi.org/10.5210/ojphi.v5i1.4593

Abstract

Prostate cancer (PC) is the most common invasive cancer among males, with most cases organ-confined at diagnosis. External beam radiation (RAD) and prostatectomy (SURG) represent the most common treatments for organ-confined PC, with RAD exposing the rectum to high-dose ionizing radiation. Using the California population for 1988-2009, we identified men treated with RAD and SURG for organ-confined PC and assessed the hazards ratio for rectal cancer five or more years following PC treatment. The adjusted Cox proportional hazards ratio was 39% higher for rectal cancer in the RAD cohort. Further analyses seek to distinguish roles of RAD dose and delivery.

Author Biography

Brice Jabo, Dept Epidemiology, Biostatistics & Population Medicine, Loma Linda University School of Public Health; Desert Sierra Cancer Surveillance Program, Region 5 of California Cancer Registry

Brice Jabo, MD is a biostatistics student at Loma Linda University School of Public Health and a Research Associate in the Desert Sierra Cancer Surveillance Program, aka Region 5 of the California Cancer Registry.

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Published

2013-03-24

How to Cite

Morgan, J. W., Jabo, B., Ghamsary, M. E., & Kazanjian, K. (2013). Mining Surveillance Data: Does Radiation Treatment of Prostate Cancer Cause Rectal Cancer?. Online Journal of Public Health Informatics, 5(1). https://doi.org/10.5210/ojphi.v5i1.4593

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Section

Poster Presentations